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| Cat. Number | H19556 |
| Chemical Name | H19556 C18 Ceramide (d18:1/18:0) 2304-81-6 |
| CAS Number | 2304-81-6 |
| Mol. Formula | C36H71NO3 |
| Mol. Weight | 566.0 |
| Qty 1 |
5mg |
| Qty 2 | 10mg |
| Appearance | A crystalline solid |
| Application Notes | A crystalline solid |
| Synonym | Cer(d18:1/18:0);Ceramide (d18:1/18:0);N-Stearoyl-D-Sphingosine |
| Solubility | DMF: 0.15 mg/mL |
| Storage condition | -20°C |
| Stability | ≥ 2 years |
| References | C18 Ceramide is an endogenous bioactive sphingolipid. It is the primary short-chain ceramide found in brain tissue whose synthesis is regulated by longevity-assurance homologue 1 (Lass1) in mice. Increased expression of C18 ceramide reduces cell growth in UM-SCC-22A squamous cell carcinoma cells. It is selectively downregulated in 32 human head and neck squamous cell carcinoma tumor tissues as compared to non-squamous tumor tissues. C18 Ceramide concentration is significantly higher in muscle tissue of type 2 diabetic patients compared with non-diabetic patients and is positively correlated to body mass index and inversely related to insulin sensitivity.[Matreya, LLC. Catalog No. 1832] C18神经酰胺是一种内源性生物活性鞘脂。 它是在大脑组织中发现的主要短链神经酰胺，其合成受小鼠长寿保证同源物1（Lass1）的调节。C18神经酰胺表达的增加降低了UM-SCC-22A鳞状细胞癌细胞的细胞生长。与非鳞状肿瘤组织相比，在32种人的头颈部鳞状细胞癌肿瘤组织中选择性地下调了α1α-β-内化。 与非糖尿病患者相比，2型糖尿病患者肌肉组织中的C18神经酰胺浓度显着更高，并且与体重指数呈正相关，与胰岛素敏感性呈负相关。3[Matreya，LLC。 货号1832] 神经酰胺是由神经鞘氨醇长链碱基与脂肪酸组成神经鞘氨脂质一种。神经酰胺(Ceramide)是以神经酰胺为骨架的一类磷脂，主要有神经酰胺磷酸胆碱和神经酰胺磷酸乙醇胺，磷脂是细胞膜的主要成分，神经酰胺（Ceramides, Cers）存在于所有的真核细胞中，对细胞分化、增殖、凋亡、衰老等生命活动具有重要调节作用。 上海惠诚生物优势提供神经酰胺系列产品,咨询订购热线：021-60498804 C16 Ceramide (d18:1(14Z)/16:0) C22 Ceramide (d18:1(14Z)/22:0) C22:1 Ceramide (d18:1(14Z)/22:1(13Z)) C24 Ceramide (d18:1(14Z)/24:0) C16 Ceramide-d7 (d18:1-d7/16:0) C18 Ceramide-d7 (d18:1-d7/18:0) C24 Ceramide-d7 (d18:1-d7/24:0) C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z)) |
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