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| Cat. Number | H10681 |
| Chemical Name | H10681 C16 Ceramide (d18:1/16:0) 24696-26-2 |
| CAS Number | 24696-26-2 |
| Category | Glycerols, Fatty Acid Derivatives & Lipids; Activators; Protein Kinase Inhibitors and Activators |
| Mol. Formula | C34H67NO3 |
| Mol. Weight | 537.90 |
| Qty 1 |
10mg |
| Qty 2 | 25mg |
| Appearance | A crystalline solid |
| Application Notes | ≥98% |
| Synonym | Cer(d18:1/16:0);Ceramide (d18:1/16:0);Palmitoyl Ceramide;N-Palmitoyl-D-erythro-Sphingosine |
| Melting Pt. | 98-99°C |
| Solubility | DMF: 0.5 mg/ml |
| Storage condition | -20°C Freezer |
| Stability | ≥ 2 years |
| References | Ceramides are generated from sphingomyelin through activation of sphingomyelinases or through the de novo synthesis pathway, which requires coordinate action of serine palmitoyl transferase and ceramide synthase. They have been shown to mediate antiproliferative responses such as apoptosis, growth arrest, differentiation, and senescence.1 C16 ceramide (d18:1/16:0) is an endogenous ceramide, generated by ceramide synthase 6 (CerS6), that acts as a lipid second messenger to regulate apoptosis and stress signaling.2 Accumulation of C16 ceramide (d18:1/16:0) through PPMP (30 μM) or MAPP (50 μM) treatment or from addition of 100 μM synthetic C16 ceramide (d18:1/16:0) induces apoptosis in neutrophil cultures via caspase- 神经酰胺是由神经鞘氨醇长链碱基与脂肪酸组成神经鞘氨脂质一种。神经酰胺(Ceramide)是以神经酰胺为骨架的一类磷脂，主要有神经酰胺磷酸胆碱和神经酰胺磷酸乙醇胺，磷脂是细胞膜的主要成分，神经酰胺（Ceramides, Cers）存在于所有的真核细胞中，对细胞分化、增殖、凋亡、衰老等生命活动具有重要调节作用。 上海惠诚生物优势提供神经酰胺系列产品,咨询订购热线：021-60498804 C16 Ceramide (d18:1(14Z)/16:0) C22 Ceramide (d18:1(14Z)/22:0) C22:1 Ceramide (d18:1(14Z)/22:1(13Z)) C24 Ceramide (d18:1(14Z)/24:0) C16 Ceramide-d7 (d18:1-d7/16:0) C18 Ceramide-d7 (d18:1-d7/18:0) C24 Ceramide-d7 (d18:1-d7/24:0) |
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