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Cat. Number
GW 6471
Chemical Name
GW 6471
CAS Number
[436159-64-7]
Mol. Formula
C35H36F3N3O5
Mol. Weight
635.68
Qty 1
10mg
Qty 2
50mg
Application Notes
>98 %
Synonym
[(2S)-2-[[(1Z)-1-Methyl-3-oxo-3-[4- (trifluoromethyl)phenyl]-1-propenyl]amino]-3-[4-[2 -(5-methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]propy l]-carbamic acid ethyl ester
Solubility
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage condition
Desiccate at +4°C
References

PPARα antagonist that inhibits activation with an IC50 value of 0.24 μM.

抑制剂

GW 6471

分子量:635.68     分子式:C35H36F3N3O5
Solubility:Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:>98 %                10mg  ,50mg 规格

Sold with the permission of GlaxoSmithKline   过氧化物酶增殖活化受体α抑制剂 GW6471    PPARα 系列产品
PPARαantagonist that inhibits activation with an IC50 value of 0.24μM.

相关产品:MK 886

分子量:472.08       分子式:C27H34ClNO2S
Solubility:Soluble to 5 mM in ethanol and to 100 mM in DMSO
Purity:>98 %             10mg  ,50mg 规格
Storage:Store at RT
CAS No:[118414-82-7]
Chemical Name: 1-[(4-Chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-α,α-dimethyl-5-(1-methylethyl)-1H-Indole-2-propanoic acid
别名:L-663,536
An inhibitor of leukotriene biosynthesis (IC50 = 3 nM in human polymorphonuclear leukocytes). Acts by inhibiting 5-lipoxygenase-activating protein (FLAP) (IC50 = 30 nM for inhibition of [125I]-L-691,678 photoaffinity labelling). Also moderately potent PPARαantagonist (IC50 = 0.5-1μM). Orally activein vivo.

PPARα 、PPARγ 及 PPARδ 系列产品点击查看

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