IV0118 InVivoPro Anti-Mouse IFNγ in vivo antibody, Clone XMG1.2_上海惠诚生物生物试剂,标准品,仪器设备,耗材,一站式服务

Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons. It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops. IFNG has antiviral, immunoregulatory, and anti-tumour properties.

Specifications

Catalog	IV0118
Product Name	InVivoPro Anti-Mouse IFNγ in vivo antibody, Clone XMG1.2
Size	1mg/5mg/25mg/50mg/100mg
Isotype	Rat IgG1 κ
Clone	XMG1.2
Target	IFNγ
Other Names	Interferon gamma, Ifng
Isotype Control Catalog Code	Rat IgG1 Isotype Control
Dilution Buffer	PBS, pH 7.2, contains no stabilizers or preservatives
Reactivity	Mouse
Host Species	Rat
How much antibody to use in vivo	200 μg per mouse; or 10 mg/kg. This range is based off the most recent publication data using the XMG1.2 clone in vivo. Each investigator should determine their own optimal working dilution for specific applications.
Background	Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons. It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops. IFNG has antiviral, immunoregulatory, and anti-tumour properties.
Applications	In vivo IFNγ neutralization, Western blot, Enzyme-linked Immunosorbent Assay
Purification	protein A or G
Storage	This antibody is stable for at least 2 months when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -20°C or -80°C. Avoid repeated freeze thaw cycles.
Shipping	2-8°C with blue ice
Concentration	Lot specific, generally ≥ 5.0 mg/ml
Shelf Life	12 months from the date of receipt if stored as recommended
Formulation	PBS Buffer, PH 7.2, with no carrier protein, or preservatives.
Sterility	0.2 μM filtered
Endotoxin	≤ 1.0 EU/mg, by the LAL method
Purity	99%