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Cat. Number
G7442
Chemical Name
G7442 GSK-343 1346704-33-3
CAS Number
1346704-33-3
Mol. Formula
C31H39N7O2
Mol. Weight
541.69
Qty 1
1mg
Qty 2
10mg
Appearance
Light Gray Powder
Application Notes
≥98%
Solubility
Ethanol (2 mg/ml), DMSO (15 mg/ml), DMF (25 mg/ml)
Storage condition
4°C
References

GSK-343 is an inhibitor of enhancer of zeste homolog 2 (EZH2) histone methyltransferase (HMT). GSK-343 exhibits anticancer activity, inhibiting cell invasion and cell growth in epithelial ovarian cancer cells.


References

Amatangelo MD, Garipov A, Li H, et al. Three-dimensional culture sensitizes epithelial ovarian cancer cells to EZH2 methyltransferase inhibition. Cell Cycle. 2013 Jul 1;12(13):2113-9. PMID: 23759589.


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