阿那白滞素 (AMG-719) Anakinra _上海惠诚生物生物试剂,标准品,仪器设备,耗材,一站式服务

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Cat. Number

HB149641

Chemical Name

阿那白滞素 (AMG-719) Anakinra

CAS Number

143090-92-0

Qty 1

10mg

Qty 2

50mg

Application Notes

>99%

References

阿那白滞素(AMG-719) Raleukin是一种重组人非糖基化白细胞介素-1(IL-1)受体拮抗剂，具有潜在的抗肿瘤活性。Raleukin与IL-1受体结合，从而阻断IL-1与其受体的结合和激活。阻断IL-1活性可能抑制下游促血管生成因子如血管内皮细胞生长因子、肿瘤坏死因子- α和IL-6的级联，从而抑制肿瘤血管生成。

订购信息:

5 mg	￥3500	In-stock
10 mg	￥5500	In-stock
50 mg	￥16500	In-stock

产品信息：

CAS RN	143090-92-0
Product Name	阿那白滞素 Anakinra
Molecular Formula	C20H23N5O7S2
Molecular Weight	509.6 g/mol
IUPAC Name	7-[[2-(2-amino-1,3-thiazol-4-yl)-2-(2,2-dimethylpropanoyloxymethoxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChI	InChI=1S/C20H23N5O7S2/c1-5-9-6-33-16-12(15(27)25(16)13(9)17(28)29)23-14(26)11(10-7-34-19(21)22-10)24-32-8-31-18(30)20(2,3)4/h5,7,12,16H,1,6,8H2,2-4H3,(H2,21,22)(H,23,26)(H,28,29)
InChI Key	HMLGSIZOMSVISS-UHFFFAOYSA-N
SMILES	CC(C)(C)C(=O)OCON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C=C)C(=O)O
Canonical SMILES	CC(C)(C)C(=O)OCON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C=C)C(=O)O
Synonyms	Anakinra;Antril;Febrile Inhibitor, IL1;IL 1 Inhibitor, Urine;IL-1 Inhibitor, Urine;IL-1Ra; IL1 Febrile Inhibitor;IL1 Inhibitor, Urine-Derived;Interleukin 1 Inhibitor, Urine;Interleukin 1 Receptor Antagonist Protein;Kineret;Urine Derived IL1 Inhibitor;Urine IL-1 Inhibitor; Urine-Derived IL1 Inhibitor;