您的位置:首页>>分析化学>>脂类分析标准品>>1256 9(Z), 11(Z)十八碳二稀酸甲酯 Methyl 9(Z), 11(Z)-octadecadienoate 822-10-6
Cat. Number
1256
Chemical Name
1256 9(Z), 11(Z)十八碳二稀酸甲酯 Methyl 9(Z), 11(Z)-octadecadienoate 822-10-6
CAS Number
822-10-6
Mol. Formula
C19H34O2
Mol. Weight
294
Qty 1
25mg
Appearance
liquid
Application Notes
96+% ethanol, methanol, hexane, chlorofrom
Synonym
Methyl ester of CLA (9 cis, 11 cis)
Solubility
ethanol, methanol, hexane, chlorofrom
Storage condition
-20°C
References

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9(E),11(E)-十八碳二烯酸甲酯 Methyl 9(E),11(E)-octadecadienoate 25mg

9(Z),11(Z)-十八碳二稀酸 9(Z),11(Z)-Octadecadienoic acid 25mg

9(Z), 11(Z)十八碳二稀酸甲酯 Methyl 9(Z), 11(Z)-octadecadienoate 25mg

Application Notes:

9(Z),11(Z)-Octadecadienoic acid is a conjugated linoleic acid (CLA), an isomer of linoleic acid. CLA is found mostly in lipids originating in ruminant animals including dairy products. It has several biological properties including anticarcinogenic activity, suppressing in vitro growth of human melanoma, colorectal, and breast cancer cells, and exhibiting anti-atherogenic activity.1 It is thought that CLA itself may not have anti-oxidant capabilities but may produce substances which protect cells from the detrimental effects of peroxides. Due to its being a minor component it is very helpful as a comparison to the major isomers 9(Z),11(E)-CLA and 10(E),12(Z)-CLA. 9(Z),11(Z)-CLA has been demonstrated to have a more potent antiproliferative effect than the more common 9(Z),11(E)-CLA isomer when incubated with human colon cancer cells.

References:
1. H. MacDonald “Conjugated Linoleic Acid and Disease Prevention: A Review of Current Knowledge” Journal of the American College of Nutrition, Vol. 19 pp. 111S-118S, 2000
2. M. Coakley, et al. “Intestinal Bifidobacteria That Produce trans-9, trans-11 Conjugated Linoleic Acid: A Fatty Acid With Antiproliferative Activity Against Human Colon SW480 and HT-29 Cancer Cells” Nutrition and Cancer, Vol. 56:1 pp. 95-102, 2006


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