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| Cat. Number | 10-4505 |
| Chemical Name | 10-4505 1-t-Butyl-3-(6-(3,5-dimethoxyphenyl)-2-(4-diethylaminobutylamino)-pyrido[2,3-d]pyrimidin-7-yl)urea 219580-11-7 |
| CAS Number | 219580-11-7 |
| Mol. Formula | C28H41N7O3 |
| Mol. Weight | 523.67 |
| Qty 1 |
5mg |
| Qty 2 | 25mg |
| Appearance | Yellow solid |
| Application Notes | 99% by HPLC NMR (Conforms) |
| Synonym | 1-t-Butyl-3-(6-(3,5-dimethoxyphenyl)-2-(4-diethylaminobutylamino)-pyrido[2,3-d]pyrimidin-7-yl)urea |
| Solubility | Soluble in DMSO. |
| Storage condition | -20℃ |
| Stability | Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. |
| References | PD173074 (219580-11-7)is an inhibitor of FGFR tyrosine kinase, and to a lesser extent VEGFR1 (IC50 values are 5 nM, 22.5 nM and 100 nM for FGFR1, FGFR3 and VEGFR respectively). Inhibition of FGFR by PD173074 promotes stem cell self renewal.2,3
References/Citations
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