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| Cat. Number | 10-2745 |
| Chemical Name | 10-2745 Fermentation product from Penicili>ium sp. 126-07-8 |
| CAS Number | 126-07-8 |
| Mol. Formula | C17H17ClO6 |
| Mol. Weight | 352.77 |
| Qty 1 |
20mg |
| Qty 2 | 100mg |
| Appearance | White solid |
| Application Notes | 98% by TLC NMR (Conforms) |
| Solubility | Soluble in DMSO (up to 40 mg/ml), in DMF (up to 50 mg/ml), or in Ethanol (up to 5 mg/ml). |
| Storage condition | RT |
| Stability | Stable for 1 year as supplied. Solutions in DMSO, ethanol, or DMF may be stored at -20° for up to 3 months. |
| References | Griseofulvin (126-07-8) is an antifungal antimitotic agent. Induces apoptosis of human germ cell tumor cells via disruption of connexin 43/tubulin association concomitant with enhanced translocation of connexin 43 from the cytoplasm to the nucleus1. Inhibits the growth of adrenocortical cancer cells in vitro2. Griseofulvin inhibits centrosome clustering, induces spindle multipolarity, mitotic arrest and cell death in multiple tumor cell lines but not in diploid fibroblasts and keratinocytes with normal centrosome content3.
References/Citations
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