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/ Products Classification 点击展开+Cat. Number | 10-2621 |
Chemical Name | 10-2621 3-[1-[3-(Dimethylamino)propyl]-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione 133053-19-7 |
CAS Number | 133053-19-7 |
Mol. Formula | C26H26N4O3 |
Mol. Weight | 442.51 |
Qty 1 |
1mg |
Qty 2 | 5mg |
Appearance | Red-orange solid |
Application Notes | 98% by HPLC NMR (Conforms) |
Synonym | 3-[1-[3-(Dimethylamino)propyl]-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione |
Solubility | Soluble in DMSO (up to 20 mg/ml) |
Storage condition | -20°C (des.) |
Stability | Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. |
References | Go-6983 (133053-19-7) potent and pan-specific, ATP-competitive protein kinase C inhibitor. PKC isotype IC50s= 7, 7, 6, 10 and 60 nM for PKC α, β, γ, δ, ζ respectively.1Suppresses stress induced HSP27 disassociation.2 Maintains rat embryonic stem cell pluripotency.3 Attenuates myocardial ischemia/reperfusion injury.4 References/Citations
1) Gschwendt et al. (1996), Inhibition od protein kinas C mu by various inhibitors. Differentiation from protein kinas C isoenzymes; FEBS Lett., 392 77 Go-6983 ,货号10-2621 上海惠诚提供1mg 5mg Go-6983,美国focus原装进口,咨询电话021-60498804 |
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