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| Cat. Number | 10-2587 |
| Chemical Name | 10-2587 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate 111974-72-2 |
| CAS Number | 111974-72-2 |
| Mol. Formula | C21H25N3O2 • 0.5C4H4O4 |
| Mol. Weight | 441.54 |
| Qty 1 |
50mg |
| Qty 2 | 500mg |
| Appearance | White solid |
| Application Notes | 98% by TLC NMR (Conforms) |
| Synonym | ICI-204636 |
| Solubility | Soluble in DMSO (up to 20 mg/ml) |
| Storage condition | RT |
| Stability | Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months |
| References | Quetiapine hemifumarate (111974-72-2) is an atypical antipsychotic agent. Antagonist at serotonin (5-HT2) and dopamine (D2) receptors, IC50s=148 and 329 nM respectively.2 Reverses depressive-like behavior and reduces DNA methyltransferase activity induced by maternal deprivation in a rat model.3Efficacious as a monotherapy in the treatment of posttraumatic stress disorder.4 References/Citations
1) Ellenbroek et al. (1996); Activity of “seroquel” (ICI 204,636) in animal models for atypical properties of antipsychotics: a comparison with clozapine; Neuropsychopharmacology 15 406
喹硫平半富马酸盐 英文名称Quetiapine hemifumarate ，货号10-2587 上海惠诚提供50mg 500mg 喹硫平半富马酸盐 Quetiapine hemifumarate，美国focus原装进口，咨询电话021-60498804 |
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