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| Cat. Number | 10-2443 |
| Chemical Name | 10-2443 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide 301836-41-9 |
| CAS Number | 301836-41-9 |
| Mol. Formula | C22H16N4O3 |
| Mol. Weight | 384.4 |
| Qty 1 |
5mg |
| Qty 2 | 25mg |
| Appearance | Yellow solid |
| Application Notes | 99% by HPLC NMR (Conforms) |
| Synonym | 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide |
| Solubility | Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 3 mg/ml). |
| Storage condition | RT |
| Stability | Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months. |
| References | SB-431542 (301836-41-9) is a potent and selective ALK4, ALK5 and ALK7 inhibitor (TGFβ superfamily Type I activin receptor-like kinase). (ALK5 IC50 = 94 nM)1,2. Inhibits TGFβ-induced proliferation of human osteosarcoma cells3. Ehances growth and integrity of embryonic stem cell-derived endothelial cells4. SB-431542 is a frequently used agent employed in numerous stem cell differentiation protocols5. Cell permeable.
References/Citations
SB-431542，货号10-2443 上海惠诚提供5mg 25mgSB-431542，美国focus原装进口，咨询电话021-60498804 |
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