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| Cat. Number | 10-2416 |
| Chemical Name | 10-2416 N-[2-Amino-6-[[(4-fluorophenyl)methyl]amino]-3-pyridinyl]carbamic acid ethyl ester maleate 75507-68-5 |
| CAS Number | 75507-68-5 |
| Mol. Formula | C15H17FN4O2 • C4H4O4 |
| Mol. Weight | 420.39 |
| Qty 1 |
50mg |
| Qty 2 | 100mg |
| Appearance | White solid |
| Application Notes | 98% by TLC NMR (Conforms) |
| Synonym | D9998 |
| Solubility | Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 4 mg/ml) |
| Storage condition | RT |
| Stability | Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months. |
| References |
flupirtine maleate (75507-68-5) activates KV7 potassium channels1, indirectly antagonizes NMDA receptors and modulates GABAA receptors2. Displays neuroprotective actions in a model of cerebral ischemia in mice and reduces apoptosis and necrosis induced by noxious stimuli. Analgesic activity.3 Active in vivo. References/Citations
1) Azad et al. (2004), The potassium channel modulator flupirtine shifts the frequency-response function of hippocampal synapses to favour LTD in mice; Neuro. Sci. Lett., 370 186
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