您的位置:首页>>生化试剂>>小分子化合物>>10-2336 8,13,13b,14-Tetrahydro-14-methylindolo[2',3'-3-4]pyrido[2,1-b]quinazolin-5-[7H]-one 518-17-2
Cat. Number
10-2336
Chemical Name
10-2336 8,13,13b,14-Tetrahydro-14-methylindolo[2',3'-3-4]pyrido[2,1-b]quinazolin-5-[7H]-one 518-17-2
CAS Number
518-17-2
Mol. Formula
C19H17N3O
Mol. Weight
303.36
Qty 1
50mg
Qty 2
250mg
Appearance
Yellow solid
Application Notes
98% by TLC
Synonym
8,13,13b,14-Tetrahydro-14-methylindolo[2',3'-3-4]pyrido[2,1-b]quinazolin-5-[7H]-one
Solubility
Soluble in DMSO (up to 5 mg/ml).
Storage condition
-20℃
Stability
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
References

Evodiamine (518-17-2) is a quinolone alkaloid isolated from Evodia rutaecarpa.1Evodia Rutaecarpa is a very popular herb used in traditional chinese medicine to treat a variety of ailments. Evodiamine has been shown to elicit a variety of biological effects including induction of apoptosis, inhibiting cancer cell proliferation, promoting cell cycle arrest in G2/M, inhibiting invasion and metastasis of cancer cells, inhibiting angiogenesis, induction of oxidative stress and subsequent apoptosis and inhibition of NF-κB.2 It also functions as an agonist of TRPV1 (EC50 = 1.03 μM)3 and acts as an anti-inflammatory agent4.

References/Citations
1) Shoji et al. (1986) Isolation of evodiamine, a powerful cardiotonic principle, from Evodia Rutaecarpa Bentham (Rutaceae); J. Pharm. Sci. 75 612
2) Jiang and Hu et al. (2009) Evodiamine: A novel anti-cancer alkaloid from Evodia rutaecarpa; Molecules, 14 1852
3) Pearce et al. (2004) Evodiamine functions as an agonist for the vanilloid receptor; Org. Biomol. Chem., 2 2281
4) Choi et al. (2006) Anti-inflammatory principles from the fruits of Evodia rutaecarpa and their cellular action mechanisms; Arch. Pharm. Res., 29 293

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吴茱萸碱  英文名称Evodiamine,货号10-2336 上海惠诚提供50mg 250mg 吴茱萸碱 Evodiamin,美国focus原装进口,咨询电话021-60498804

吴茱萸碱  英文名称Evodiamine,货号10-2336 上海惠诚提供50mg 250mg 吴茱萸碱 Evodiamin,美国focus原装进口,咨询电话021-60498804

 

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