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/ Products Classification 点击展开+Cat. Number | 10-2315 |
Chemical Name | 10-2315 (1R)-2,3-Dihydro-N-2-propynyl-1H-inden-1-amine methanesulfonate 161735-79-1 |
CAS Number | 161735-79-1 |
Mol. Formula | C12H13N • CH3SO3H |
Mol. Weight | 267.34 |
Qty 1 |
50mg |
Qty 2 | 250mg |
Appearance | White solid |
Application Notes | 98% by TLC NMR (Conforms) |
Synonym | TVP-1012; Azilect |
Solubility | Soluble in DMSO (up to 50 mg/ml), in Water (up to 50 mg/ml), or in Ethanol (up to 30 mg/ml) |
Storage condition | -20°C (des.) |
Stability | Stable for 2 years as supplied. Solutions in DMSO, distilled water or ethanol may be stored at -20°C for up to 1 month. |
References | Rasagiline mesylate (161735-79-1) is a potent, irreversible monoamine oxidase (MAO) inhibitor selective for MAO-B (IC50=4.43 nM) over MAO-A (IC50=412 nM).1Parkinson’s disease therapeutic.2 Displays neuroprotective and neurorestorative properties in a Parkinson’s disease zebrafish model.3 Prevents α-synuclein-induced dopaminergic neuronal death and rescues TrkB neurotrophic signaling.4 Enhances BDNF levels and is neuroprotective in Parkinson’s disease models.5 References/Citations
1) Youdim et al. (2001), Rasagiline [N-propargyl-1R(+)-aminoindan], a selective and potent inhibitor of mitochondrial monoamine oxidase B; Br. J. Pharmacol., 132 500 雷沙吉兰甲磺酸盐 英文名称Rasagiline mesylate ,货号10-2315 上海惠诚提供50mg 250mg 雷沙吉兰甲磺酸盐 Rasagiline mesylate,美国focus原装进口,咨询电话021-60498804 雷沙吉兰甲磺酸盐 英文名称Rasagiline mesylate ,货号10-2315 上海惠诚提供50mg 250mg 雷沙吉兰甲磺酸盐 Rasagiline mesylate,美国focus原装进口,咨询电话021-60498804
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