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| Cat. Number | 10-2120 |
| Chemical Name | 10-2120 硼替佐米 Bortezomib 179324-69-7 |
| CAS Number | 179324-69-7 |
| Mol. Formula | C19H25BN4O4 |
| Mol. Weight | 384.25 |
| Qty 1 |
5mg |
| Qty 2 | 25mg |
| Appearance | White solid |
| Application Notes | 98% by TLC NMR (conforms) |
| Synonym | MG-341, PS-341,N-(2-Pyrazine)carbonyl-L-phenylalanine-L-leucine boronic acid |
| Solubility | Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 35 mg/ml). |
| Storage condition | -20℃ |
| Stability | Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months. |
| References | Potent and selective proteasome inhibitor (Ki=0.6 nM). Inhibits proliferation of a number of tumor cell lines (IC50=7 nM). Inhibits TNFα synthesis and FGF-induced angiogenesis. Clinically useful agent for treatment of multiple myeloma.3 Shows promise in the treatment of neurodegenerative diseases in which low-expressing proteins such as IKAP/hELP1 in familial dysautonomia are preserved.4 Reversible. Cell permeable.
References/Citations
硼替佐米 英文名称Bortezomib ，货号10-2120 上海惠诚提供5mg 25mg 硼替佐米 Bortezomib，美国focus原装进口，咨询电话021-60498804 硼替佐米 英文名称Bortezomib ，货号10-2120 上海惠诚提供5mg 25mg 硼替佐米 Bortezomib，美国focus原装进口，咨询电话021-60498804
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