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Cat. Number
10-2110
Chemical Name
曲古抑菌素A. Trichostatin A
CAS Number
58880-19-6
Mol. Formula
C17H,sub>22N2O3
Mol. Weight
302.38
Qty 1
1mg
Qty 2
5mg
Appearance
Tan solid
Application Notes
99% by HPLC NMR (Conforms)
Synonym
TSA,(2E,4E,6R)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
Solubility
Soluble in DMSO (up to 15 mg/ml), or in Ethanol (up to 3 mg/ml).
Storage condition
-20℃
Stability
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
References

Trichostatin A (58880-19-6) is a potent and selective histone deacetylase (HDAC) inhibitor (Ki = 3.4 nM). Induces reversion of ras transformed cells to normal morphology. Trichostatin A induces dedifferentiation of primordial germ cells into embryonic germ cells. Cell permeable and active in vivo.

References/Citations
1) Yoshida et al. (1990), Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A ; J. Biol. Chem., 265 17174
2) Futamura et al. (1995), Trichostatin A inhibits both ras-induced neurite outgrowth of PC12 cells and morphological transformation of NIH3T3 cells; Oncogene, 10 1119
3) Durcova-Hills et al. (2008), Reprogramming Primordial Germ Cells into Pluripotent Stem Cells; PLoS-One, 3 e3531

Focus Biomolecules cell signaling reagent supplier, chemical structure of Trichostatin A | HDAC inhibitor | CAS 58880-19-6

曲古抑菌素A.  英文名称Trichostatin A ,货号10-2110 上海惠诚提供1mg 5mg 曲古抑菌素A. Trichostatin A,美国focus原装进口,咨询电话021-60498804
曲古抑菌素A.  英文名称Trichostatin A ,货号10-2110 上海惠诚提供1mg 5mg 曲古抑菌素A. Trichostatin A,美国focus原装进口,咨询电话021-60498804
 
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