您的位置:首页>>生化试剂>>小分子化合物>>霉酚酸 Mycophenolic acid
Cat. Number
10-2087
Chemical Name
霉酚酸 Mycophenolic acid
CAS Number
24280-93-1
Mol. Formula
C17H20O6
Mol. Weight
320.35
Qty 1
100mg
Qty 2
500mg
Appearance
White solid
Application Notes
98% by TLC NMR (Conforms)
Synonym
NSC129185,6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexanoic acid
Solubility
Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 30 mg/ml).
Storage condition
RT
Stability
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
References

Mycophenolic acid (24280-93-1) is an immunomodulator1 that blocks the biosynthesis of guanine nucleotides via inhibition of inosine 5'-monophosphate dehydrogenase. This in turn suppresses the production of proinflammatory cytokines, nitric oxide and LDH in macrophages2,3. Inhibits IL-2 -dependent T cell proliferation4.

References/Citations
1) Eugui et al. (1991), Lymphocyte-selective cyostatic and immunosuppressive effects of mycophenolic acid in vitro: role of deoxyguanosine nucleotide depletion; Scand. J. Immunol., 33 161
2) Jonsson et al. (2002), Mycophenolic acid inhibits inosine 5'-monophosphate dehydrogenase and suppresses production of pro-inflammatory cytokines, nitric oxide and LDH in macrophages; Cell. Immunol., 216 93
3) Allison et al. (1993), Mechanisms of action of mycophenolic acid; Ann. NY Acad. Sci., 696 63
4) Quemeneur et al. (2002), Mycophenolic acid inhibits IL-2-dependent T cell proliferation, but not IL-2-dependent survival and sensitization to apoptosis; J. Immunol., 169 2747

Focus Biomolecules supplier, chemical structure of Mycophenolic acid | Immunosuppressant | CAS 24280-93-1

霉酚酸 英文名称Mycophenolic acid ,货号10-2087 上海惠诚提供100mg 500mg 霉酚酸 Mycophenolic acid,美国focus原装进口,咨询电话021-60498804

在线咨询 联系方式 二维码

服务热线

021-60498804

扫一扫,关注我们