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| Cat. Number | 10-2086 |
| CAS Number | 128794-94-5 |
| Mol. Formula | C23H31NO7 |
| Mol. Weight | 433.51 |
| Qty 1 |
50mg |
| Qty 2 | 250mg |
| Appearance | White solid |
| Synonym | 6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid 2-(4-morpholinyl)ethyl ester |
| Solubility | Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 4 mg/ml). |
| Storage condition | RT (des.) |
| Stability | Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month. |
| References | Mycophenolate mofetil (128794-94-5) is a mycophenolic acid prodrug. Immunosuppressive agent useful in prevention of organ allograft rejection.1 Is metabolized to mycophenolic acid in vivo which acts by inhibiting the biosynthesis of guanine nucleotides via inhibition of inosine 5’-monophosphate dehydrogenase, suppressing the production of proinflammatory cytokines, nitric oxide and LDH in macrophages.2,3 IL-2-dependent T cell proliferation is also inhibited.4 Inhibits microglial and astrocytic activation reducing cell death after neuronal injury.5 Active in vivo. References/Citations
1) Allison & Eugui (1996), Purine metabolism and immunosuppressive effects of mycophenolate mofetil (MMF); Clin. Transplant., 10 77
Mycophenolate mofetil ，货号10-2086 上海惠诚提供250mg 50mg Mycophenolate mofetil，美国focus原装进口，咨询电话021-60498804
Mycophenolate mofetil ，货号10-2086 上海惠诚提供250mg 50mg Mycophenolate mofetil，美国focus原装进口，咨询电话021-60498804
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