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/ Products Classification 点击展开+Cat. Number | 10-2079 |
Chemical Name | 离子霉素钙 Ionomycin calcium |
CAS Number | 56092-81-0 |
Mol. Formula | C41H72O9 |
Mol. Weight | 709.01 |
Qty 1 |
1mg |
Qty 2 | 5mg |
Appearance | Yellow oil |
Application Notes | 98% by TLC NMR (Conforms) |
Solubility | Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 10 mg/ml). |
Storage condition | -20℃ |
Stability | Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months. |
References | Ionomycin (56092-81-0) is a highly selective nonfluorescent calcium (Ca2+) ionophore.1 Induces a rapid rise in cytosolic Ca2+ in human neutrophils which is due to both release from cytosolic Ca2+ stores as well as Ca2+ influx.2 It activates (2 μM) and primes (20-200 nM) neutrophil NADPH oxidase2. Down regulates beta-catenin/Tcf signaling in a colon cancer cell line via suppressing the binding of Tcf to its specific DNA-binding site.3 In rat hepatoma cells, sub-lethal ionomycin activates the stress response by activating SAPK/JNK and HSF/HSE interaction leading to upregulation of HSP70 biosynthesis.4
References/Citations
离子霉素钙 英文名称Ionomycin calcium ,货号10-2079 上海惠诚提供1mg 5mg 离子霉素钙 Ionomycin calcium,美国focus原装进口,咨询电话021-60498804 |