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Cat. Number
10-1455
Chemical Name
ML-324
CAS Number
1222800-79-4
Mol. Formula
C21H23N3O2 HCl
Mol. Weight
385.9
Qty 1
5mg
Qty 2
25mg
Appearance
Olive solid
Application Notes
98% by TLC NMR (Conforms)
Synonym
N-(3-(Dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide hydrochloride
Solubility
Soluble in DMSO (up to 20 mg/ml) or in Water (up to 25 mg/ml).
Storage condition
-20°C (des.)
Stability
Stable for 1 year as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
References

ML-324 (1222800-79-4) inhibits JMJD2 histone demethylases. Represses the expression of viral (HCMV and HSV-1) immediate early genes (IC50 ~ 10 μM) and abrogates infection. ML-324 represses the reactivation of HSV from the latent state in sensory neurons1.

References/Citations
1) Liang et al. (2013), Targeting the JMJD2 histone demethylases to epigenetically control herpesvirus infection and reactivation from latency; Sci. Transl. Med., 5 167ra5

Focus Biomolecules cell signaling reagent supplier, chemical structure of ML-324 | JMJD2 inhibitor | CAS 1222800-79-4

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