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Cat. Number
10-1430
Chemical Name
CVPA
CAS Number
37710-81-9
Mol. Formula
C12H10O4
Mol. Weight
218.21
Qty 1
10mg
Qty 2
50mg
Appearance
White solid
Application Notes
97% by TLC NMR (Conforms)
Synonym
3,3'-(1,3-Phenylene)bis(2-propenoic acid),3-[3-(2-Carboxy-vinyl)-phenyl]-acrylic acid
Solubility
Soluble in DMSO (up to 25 mg/ml).
Storage condition
RT (des.)
Stability
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
References

CVPA (37710-81-9) is an aquaporin-1 inhibitor (IC50 = 8.1 μM) discovered by molecular docking against the extracellular domain of human aquaporin-1 followed by experimental testing in a Xenopus oocyte swelling assay.1

References/Citations
1) Seeliger et al. (2012), Discovery of novel human aquaporin-1 blockers; ACS Chem. Biol., 8 249

Focus Biomolecules cell signaling reagent supplier, chemical structure of CVPA | Aquaporin 1 inhibitor | CAS 37710-81-9

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