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| Cat. Number | 10-1407 |
| Chemical Name | PP2 |
| CAS Number | 172889-27-9 |
| Mol. Formula | C15H16ClN5 |
| Mol. Weight | 301.78 |
| Qty 1 |
5mg |
| Qty 2 | 25mg |
| Appearance | Off-white solid |
| Application Notes | 98% by TLC NMR (Conforms) |
| Synonym | 3-(4-Chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Solubility | Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 3 mg/ml with warming). |
| Storage condition | -20°C |
| Stability | Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month. |
| References | PP2 (172889-27-9) is a potent and selective Src family kinase inhibitor. Inhibits Lck(IC50=4 nM); Fyn (IC50=5 nM); Hck (IC50=5 nM). It displays weak inhibition of EGFR (IC50=480 nM) and no inhibition of ZAP-70 (IC50> 100 μM) and JAK2 (IC50> 50 μM).1 PP2 is a useful probe for exploring the involvement of Src family kinases in signal transduction pathways.2
References/Citations
PP2，货号10-1407 上海惠诚提供5mg 25mg PP2，美国focus原装进口，咨询电话021-60498804 |
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