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| Cat. Number | 10-1380 |
| Chemical Name | Ferrostatin-1 |
| CAS Number | 347174-05-4 |
| Mol. Formula | C15H22N2O2 |
| Mol. Weight | 262.35 |
| Qty 1 |
5mg |
| Qty 2 | 25mg |
| Appearance | Tan solid |
| Application Notes | 98% by TLC NMR (Conforms) |
| Synonym | Ethyl 3-amino-4-(cyclohexylamino)benzoate |
| Solubility | Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 100 mg/ml). |
| Storage condition | RT |
| Stability | Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month. |
| References | Ferrostatin-1 (347174-05-4) inhibits ferroptosis (EC50=60 nM), an iron-dependent form of nonapoptotic cell death.1 Potent inhibitor of ferroptosis in cancer cells and glutamate-induced cell death in organotypic rat brain slices.1 Blocks the cytotoxic effects of sorafenib in hepatocellular carcinoma cells.2 Ferrostatin-1 inhibits oxidative lipid damage and cell death in diverse disease models3 and prevents apoptosis of renal proximal tubular cells induced by reactive oxygen species4.
References/Citations
Ferrostatin-1 ，货号10-1380 上海惠诚提供5mg 25mg Ferrostatin-1，美国focus原装进口，咨询电话021-60498804 |
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