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| Cat. Number | 10-1351 |
| Chemical Name | WP-1130 |
| CAS Number | 856243-80-6 |
| Mol. Formula | C19H18BrN3O |
| Mol. Weight | 384.28 |
| Qty 1 |
5mg |
| Qty 2 | 25mg |
| Appearance | Yellow solid |
| Application Notes | 98% by TLC NMR (Conforms) |
| Synonym | Degrasyn,(S,E)-3-(6-bromopyridin-2-yl)-2-cyano-N-(1-phenylbutyl)acrylamide |
| Solubility | Soluble in DMSO (up to 45 mg/ml), or in Ethanol (up to 25 mg/ml). |
| Storage condition | -20℃ |
| Stability | Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. |
| References | WP-1130 (856243-80-6) is a novel DUB inhibitor directly inhibiting USP9x, USP5, USP14 and UCH37 inducing rapid accumulation of polyubiquitinated proteins. Triggers tumor cell apoptosis.1 Blocks Jak2 signaling via Jak2 ubiquitination.2 WP-1130 causes ablation of the oncogenic transcription factor ERG in prostate cancer cells.3
References/Citations
WP-1130 ，货号10-1351 上海惠诚提供5mg 25mg WP-1130，美国focus原装进口，咨询电话021-60498804 |
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