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/ Products Classification 点击展开+Cat. Number | 10-1311 |
Chemical Name | MLN4924 |
CAS Number | 905579-51-3 |
Mol. Formula | C21H25N5O4S |
Mol. Weight | 443.53 |
Qty 1 |
1mg |
Qty 2 | 5mg |
Appearance | White solid |
Application Notes | 98% by TLC NMR (Conforms) |
Synonym | ((1S,2S,4R)-4-(4-(((S)-2,3-dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate |
Solubility | Soluble in DMSO (up to 10 mg/ml). |
Storage condition | -20°C (des.) |
Stability | Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. |
References | MLN4924 (905579-51-3) is a potent and selective NEDD8-activating enzyme (NAE) inhibitor. Disrupts cullin-RING ligase-mediated protein turnover leading to apoptosis in human tumor cells. Supresses the growth of tumor xenografts in mice. Cell permeable.
References/Citations
MLN4924 ,货号10-1311 上海惠诚提供10mg 50mg MLN4924,美国focus原装进口,咨询电话021-60498804 |
下一个:SL-01上一个:GSK-690693 HCl |