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Cat. Number
10-1298
Chemical Name
JNJ-1661010
CAS Number
681136-29-8
Mol. Formula
C19H19N5OS
Mol. Weight
365.46
Qty 1
10mg
Qty 2
50mg
Appearance
Off-white solid
Application Notes
98% by TLC NMR (Conforms)
Synonym
N-Phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)-1-piperazinecarboxamide,4-(3-Phenyl-[1,2,4]thizdiazol-5-yl)-piperazine-1-carboxylic acid phenylamide
Solubility
Soluble in DMSO (up to 25 mg/ml).
Storage condition
RT
Stability
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
References

JNJ-1661010 (681136-29-8) is a potent and selective FAAH inhibitor. Initially forms a covalent adduct with FAAH but is slowly released, IC50 = 12 nM. 100-fold selectivity for FAAH-1 over FAAH-2. Cell permeable and active in vivo. JNJ-1661010 displays analgesic activity in various animal models.

References/Citations
1) Karbarz et al. (2009), Biochemical and biological properties of 4-(3-phenyl-[1,2,4]thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a mechanism-based inhibitor of fatty acid amide hydrolase; Anesth. Analg., 108 316

Focus Biomolecules cell signaling reagent supplier, chemical structure of JNJ-1661010 | FAAH inhibitor | CAS 681136-29-8

JNJ-1661010 ,货号10-1298 上海惠诚提供10mg 50mg JNJ-1661010,美国focus原装进口,咨询电话021-60498804

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