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Cat. Number
10-1154
Chemical Name
Reversine
CAS Number
656820-32-5
Mol. Formula
C21H27N7O
Mol. Weight
383.5
Qty 1
1mg
Qty 2
5mg
Appearance
Off-white solid
Application Notes
98% by TLC NMR (Conforms)
Synonym
2-(4-Morpholinoanilino)-6-cyclohexylaminopurine
Solubility
Soluble in DMSO (up to 7 mg/ml).
Storage condition
-20°C (des.)
Stability
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months
References

Reversine (656820-32-5) induces differentiated myogenic-lineage-committed cells to become multipotent mesenchymal progenitor cells.1-2 Acts as a selective human A3adenosine receptor antagonist (Ki = 0.66 μM).3 Cell permeable.

References/Citations
1) Chen et al. (2004), Dedifferentiation of lineage-committed cells by a small molecule; J. Am. Chem. Soc., 126 410
2) Chen et al. (2007), Reversine increases the plasticity of lineage-committed mammalian cells; Proc. Natl. Acad. Sci. USA, 104 10482
3) Perreira et al. (2005), Reversine and its 2-substituted adenine derivatives as potent and selective A3 adenosine receptor antagonists; J. Med. Chem., 48 4910

Focus Biomolecules supplier, Reversine | Reverses differentiated cells to multipotent stem cells | CAS 656820-32-5

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