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Cat. Number
10-1103
Chemical Name
FK-506
CAS Number
104987-11-3
Mol. Formula
C44H69NO12
Mol. Weight
804.04
Qty 1
50mg
Qty 2
100mg
Appearance
White solid
Application Notes
98% by TLC NMR (Conforms)
Synonym
Tacrolimus,
Solubility
Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 50 mg/ml).
Storage condition
-20℃
Stability
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
References

FK-506 (104987-11-3) induces immunosuppression by inhibiting T cell proliferation. Inhibits FKBP12 and calcineurin (IC50 ~ 1 nM). Cell permeable.

References/Citations
1) Yu et al. (2006), Effects of cyclosporine A, FK506 and rapamycin on clacineurin phosphatase activity in mouse brain; IUBMB Life, 58 429

Focus Biomolecules cell signaling reagent supplier, chemical structure of FK-506 | FKBP inhibitor | CAS 104987-11-3

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