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Cat. Number
10-1100
Chemical Name
扎鲁司特 Zafirlukast
CAS Number
107753-78-6
Mol. Formula
C31H33N3O6S
Mol. Weight
575.69
Qty 1
10mg
Qty 2
50mg
Appearance
White or pink solid
Application Notes
98% by TLC NMR (Conforms)
Synonym
ICI-204219
Solubility
Soluble in DMSO (up to 10 mg/ml).
Storage condition
RT
Stability
Stable for 2 years as supplied. Protect from exposure to moisture. Solutions in DMSO may be stored at -20°C for up to 3 months.
References

Zafirlukast (107753-78-6) is a competitive and selective leukotriene receptor antagonist1. Also inhibits calcium ionophore induced production of leukotriene B4and leukotriene C4, which suggests a potential 5-LO inhibitory activity2. Cell permeable and orally active.

References/Citations
1) Adkins and Brogden, (1998), Zafirlukast. A review of its pharmacology and therapeutic potential in the management of asthma; Drugs, 55 121
2) Woszczek et al., (2010), Concentration-dependent noncysteinyl leukotriene type 1 receptor-mediated inhibitory activity of leukotriene receptor antagonists; J. Immunol. 184 2218
3) Wyttenbach & Kuentz (2017), Glass-forming ability of compounds in marketed amorphous drug products; Eur. J. Pharm. and Biopharm., 112 204 [Focus Citation]

Focus Biomolecules offers cell signaling reagent, Zafirlukast | HSP70 inhibitor, leukotriene antagonist | CAS 107753-78-6

扎鲁司特  英文名称Zafirlukast ,货号10-1100上海惠诚提供10mg 50mg 扎鲁司特 Zafirlukast,美国focus原装进口,咨询电话021-60498804

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