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| Cat. Number | 10-1030 |
| Chemical Name | ZM-336372 |
| CAS Number | 208260-29-1 |
| Mol. Formula | C23H23N3O3 |
| Mol. Weight | 389.46 |
| Qty 1 |
5mg |
| Qty 2 | 25mg |
| Appearance | Off-white solid |
| Application Notes | 98% by TLC NMR (Conforms) |
| Synonym | 3-(Dimethylamino)-N-[3-[(4-hydroxybenzoyl)-amino]-4-methylphenyl]benzamide |
| Solubility | Soluble in DMSO (up to 50 mg/ml). |
| Storage condition | -20°C |
| Stability | Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. |
| References | ZM-336372 (208206-29-1) is a potent and specific inhibitor of the protein kinase c-Raf (IC50=70nM). Has no significant effect on many other protein kinases tested (even at 50μM) with the exception of p38 (SAPK2α) (IC50=2μM) and SAPK2β (p38β) (IC50=2μM). ZM-336372 induces a paradoxical >100-fold activation of c-Raf in whole cells. Induces apoptosis in a variety of cell lines. Cell permeable.
References/Citations
ZM-336372 ，货号10-1030 上海惠诚提供5mg 25mg ZM-336372，美国focus原装进口，咨询电话021-60498804 |
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