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/ Products Classification 点击展开+Cat. Number | 10-1026 |
Chemical Name | GF-109203X |
CAS Number | 133052-90-1 |
Mol. Formula | C25H24N4O2 |
Mol. Weight | 412.49 |
Qty 1 |
5mg |
Qty 2 | 25mg |
Appearance | Orange solid |
Application Notes | 98% by TLC NMR (Conforms) |
Synonym | Go 6850; Bisindolylmaleimide I,2-[1-(3-Dimethylaminopropyl)indol-3-yl]-3-(indol-3-yl) maleimide |
Solubility | Soluble in DMSO (up to 10 mg/ml). |
Storage condition | RT |
Stability | Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 6 months. |
References | GF-109203X (133052-90-1) is a potent and selective protein kinase C inhibitor (IC50 = 10 nM; cAMP-dependent protein kinase IC50 = 2 μM and phosphorylase kinase IC50= 0.7 μM). Inactive against the tyrosine kinases EGFR, PGDFR and Insulin receptor. Potent inhibitor of GSK-3β in cell lysates (IC50 = 360nM) and GSK-3β immunoprecipitates (IC50 = 170nM) derived from rat epididymal adipocytes.2 Cell permeable.
References/Citations
GF-109203X ,货号10-1026 上海惠诚提供5mg 25mg GF-109203X,美国focus原装进口,咨询电话021-60498804
GF-109203X ,货号10-1026 上海惠诚提供5mg 25mg GF-109203X,美国focus原装进口,咨询电话021-60498804
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