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Cat. Number
10-1015
Chemical Name
酮康唑(碱) Ketoconazole (base)
CAS Number
65277-42-1
Mol. Formula
C26H28Cl2N4O4
Mol. Weight
531.43
Qty 1
100mg
Qty 2
500mg
Appearance
Off-white solid
Application Notes
>98% by TLC
Synonym
(±)-1-[4-(4-{[-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethan-1-one
Solubility
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
Storage condition
RT
Stability
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
References

Ketoconazole (65277-42-1) is a broad spectrum antifungal agent acting via inhibition of cytochrome P450 14-α-demethylase.1 Ketoconazole has been shown to inhibit CYP3A and CYP1A1.2

References/Citations
1) Loose et al. (1983) Ketoconazole blocks adrenal steroidogenesis by inhibiting cytochrome P450-dependent enzymes; J. Clin. Invest. 71 1495
2) Sai et al. (2000) Assessment of specificity of eight chemical inhibitors using cDNA-expressed cytochromes P450. Xenobiotica 30 327

Focus Biomolecules cell signaling reagent supplier, structure Ketoconazole | Cytochrome P450 inhibitor | CAS 65277-42-1

酮康唑(碱)  英文名称Ketoconazole (base) ,货号10-1015 上海惠诚提供100mg 500mg 酮康唑(碱) Ketoconazole (base),美国focus原装进口,咨询电话021-60498804

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