服务热线
021-60498804
| Cat. Number | FGF19 |
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Chemical Name | FGF19 Protein, Human, Recombinant |
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| References | FGF19 Protein, Human, Recombinant 也称为FGF-19，是成纤维细胞生长因子（FGF）家族的成员。 FGF家族成员具有广泛的促有丝分裂和细胞存活活性，并参与多种生物过程。
上海惠诚生物提供FGF19 Protein, Human, Recombinant (Native) 以及各类细胞因子，同时推出CHO稳定细胞株开发技术服务方案，详情咨询电话021-60498804.
Background Information：
FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF19 interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by KL, KLB and heparan sulfate glycosaminoglycans that function as coreceptors. It interacts with KL and KLB directly. However, it interacts with FGFR4 in the presence of heparin, KL or KLB. FGF19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. It also stimulates glucose uptake in adipocytes.
上海惠诚生物提供FGF19 Protein, Human, Recombinant (Native) 以及各类细胞因子，同时推出CHO稳定细胞株开发技术服务方案，详情咨询电话021-60498804.
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Copyright © 2022 上海惠诚生物科技有限公司
沪ICP备2021037845号-6
