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| Cat. Number | D1629 |
| Chemical Name | 脱氢表雄酮 DHEA |
| CAS Number | 53-43-0 |
| Mol. Formula | C19H28O2 |
| Mol. Weight | 288.42 |
| Qty 1 |
5g |
| Qty 2 | 25g |
| Appearance | White Crystal Powder |
| Application Notes | ≥98% |
| Synonym | Prasterone, DHEA, Dehydroepiandosterone |
| Melting Pt. | 149-151°C |
| Solubility | Soluble in ethanol or DMSO. Insoluble in water. |
| Storage condition | Ambient |
| References | Dehydroepiandrosterone (DHEA) is an endogenous steroid hormone produced in the adrenal glands, gonads, and brain; it is an intermediate in the synthesis of estrogens and androgens. DHEA exhibits neuroprotective, cognition enhancing, anti-androgenic, anticancer, anti-metastatic, antiepileptic/anticonvulsant, anti-asthma, antacid, and anti-ulcerative activities. 参考文献： do Vale S, Selinger L, Martins JM, et al. The relationship between dehydroepiandrosterone (DHEA), working memory and distraction--a behavioral and electrophysiological approach. PLoS One. 2014 Aug 8;9(8):e104869. PMID: 25105970. Ortega-Calderón YN, López-Marure R. Dehydroepiandrosterone inhibits proliferation and suppresses migration of human cervical cancer cell lines. Anticancer Res. 2014 Aug;34(8):4039-44. PMID: 25075027. Xu L, Xiang X, Ji X, et al. Effects and mechanism of dehydroepiandrosterone on epithelial-mesenchymal transition in bronchial epithelial cells. Exp Lung Res. 2014 Jun;40(5):211-21. PMID: 24784499. Eleawa S, Bin-Jaliah I, Alkhateeb M, et al. The impact of dehydroepiandrosterone on indomethacin-induced gastric lesions in rats. Acta Physiol Hung. 2014 Mar;101(1):77-87. PMID: 24631796. Engdahl C, Lagerquist MK, Stubelius A, et al. Role of androgen and estrogen receptors for the action of dehydroepiandrosterone (DHEA). Endocrinology. 2014 Mar;155(3):889-96. PMID: 24424045. Neunzig J, Bernhardt R. Dehydroepiandrosterone sulfate (DHEAS) stimulates the first step in the biosynthesis of steroid hormones. PLoS One. 2014 Feb 21;9(2):e89727. PMID: 24586990. Espinoza J, Montaño LM, Perusquía M. Nongenomic bronchodilating action elicited by dehydroepiandrosterone (DHEA) in a guinea pig asthma model. J Steroid Biochem Mol Biol. 2013 Nov;138:174-82. PMID: 23727130. Mishra M, Singh R, Mukherjee S, et al. Dehydroepiandrosterone's antiepileptic action in FeCl3-induced epileptogenesis involves upregulation of glutamate transporters. Epilepsy Res. 2013 Sep;106(1-2):83-91. PMID: 23891458. |
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