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| Cat. Number | C9644 |
| Chemical Name | Cylindrospermopsin |
| CAS Number | 143545-90-8 |
| Mol. Formula | C15H21N5O7S |
| Mol. Weight | 415.42 |
| Qty 1 |
100 µg |
| Appearance | Clear film |
| Application Notes | ≥95% |
| Solubility | Soluble in Methanol and DMSO |
| Storage condition | -20°C |
| References | Cylindrospermopsin is a cyanotoxin that was initially produced by the cyanobacterium Cylindrospermopsis raciborskii. Cylindrospermopsin inhibits protein and glutathione synthesis in vitro, inducing oxidative stress, double-stranded DNA breaks, and cell cycle arrest. 参考文献： Gutiérrez-Praena D, Risalde MA, Pichardo S, et al. Histopathological and immunohistochemical analysis of Tilapia (Oreochromis niloticus) exposed to cylindrospermopsin and the effectiveness of N-Acetylcysteine to prevent its toxic effects. Toxicon. 2013 Nov 28;78C:18-34. [Epub ahead of print]. PMID: 24291634. Guzmán-Guillén R, Prieto AI, Moreno I, et al. Cyanobacterium producing cylindrospermopsin cause histopathological changes at environmentally relevant concentrations in subchronically exposed tilapia (Oreochromis niloticus). Environ Toxicol. 2013 Sep 2. [Epub ahead of print]. PMID: 24000190. Alja Š, Filipič M, Novak M, et al. Double strand breaks and cell-cycle arrest induced by the cyanobacterial toxin cylindrospermopsin in HepG2 cells. Mar Drugs. 2013 Aug 21;11(8):3077-90. PMID: 23966038. López-Alonso H, Rubiolo JA, Vega F, et al. Protein synthesis inhibition and oxidative stress induced by cylindrospermopsin elicit apoptosis in primary rat hepatocytes. Chem Res Toxicol. 2013 Feb 18;26(2):203-12. PMID: 23270326. |
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