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Cat. Number
C9613
Chemical Name
环孢菌素D. Cyclosporin D
CAS Number
63775-96-2
Mol. Formula
C63H113N11O12
Mol. Weight
1216.64
Qty 1
1mg
Qty 2
5mg
Appearance
White Crystalline Powder
Application Notes
≥98%
Synonym
Val2-cyclosporine
Melting Pt.
148-151°C
Solubility
Soluble in methanol, ethanol, acetone, ether, ethyl acetate or chloroform. Insoluble in water.
Storage condition
Ambient
References

Cyclosporin D is a cyclosporin metabolite that weakly inhibits calmodulin and displays little immunosuppressive activity. Cyclosporin D exhibits anti-parasitic and antimalarial activities, inhibiting Plasmodium development in vitro and in vivo.

参考文献:

Uadia PO, Ezeamuzie IC, Ladan MJ, et al. Antimalarial activity of cyclosporins A, C and D. Afr J Med Med Sci. 1994 Mar;23(1):47-51. PMID: 7839946.

Sadeg N, Pham-Huy C, Rucay P, et al. In vitro and in vivo comparative studies on immunosuppressive properties of cyclosporines A, C, D and metabolites M1, M17 and M21. Immunopharmacol Immunotoxicol. 1993 Mar-Jun;15(2-3):163-77. PMID: 8349948.

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