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Cat. Number
H9661
Chemical Name
Hypocrellin A
CAS Number
77029-83-5
Mol. Formula
C30H26O10
Mol. Weight
546.52
Qty 1
1mg
Appearance
White to off white powder
Application Notes
≥77%, contains ~16% B
Synonym
Hypocrellin
Solubility
Soluble in heptane, DMSO.
Storage condition
4°C
References

Hypocrellin A exhibits antibacterial and immunomodulatory activities. In vitro, hypocrellin A inhibits MHC II antigen presentation but not MHC I antigen presentation. Additionally, this compound increases levels of ROS and induces cell wall damage in Staphylococcus, Salmonella, Escherichia, and Bacillus. Contains ~16 % hypocrellin B

参考文献:

Du W, Sun C, Liang Z, et al. Antibacterial activity of hypocrellin A against Staphylococcus aureus. World J Microbiol Biotechnol. 2012 Nov;28(11):3151-7. PMID: 22864599.

Park S, Im SA, Kim KH, et al. Immunomodulatory Effects of Hypocrellin A on MHC-restricted Antigen Processing. Immune Netw. 2011 Dec;11(6):412-5. PMID: 22346783.

Su Y, Sun J, Rao S, et al. Photodynamic antimicrobial activity of hypocrellin A. J Photochem Photobiol B. 2011 Apr 4;103(1):29-34. PMID: 21300554.

Xu Y, Zhang Z, Zhang H. Raman spectroscopic study of DNA after photosensitive damage caused by hypocrellins A and B. Sci China C Life Sci. 1998 Aug;41(4):360-6. PMID: 18726251.

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