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| Cat. Number | C0221 |
| Chemical Name | 咖啡因 Caffeine |
| CAS Number | 58-08-2 |
| Mol. Formula | C8H10N4O2 |
| Mol. Weight | 194.19 |
| Qty 1 |
10g |
| Qty 2 | 50g |
| Appearance | White Crystal Powder |
| Application Notes | ≥98% |
| Synonym | Coffeine, Thein, Guaranine, Methyltheobromine, No-Doz |
| Melting Pt. | 238°C |
| Solubility | Soluble in ethyl acetate or pyrrole. Slightly soluble in water (20 mg/mL), solubility is increased by adding dilute acid. Slightly soluble in ethanol (13 mg/mL). |
| Storage condition | Ambient |
| References | Caffeine is a xanthine alkaloid found in coffee, tea, and many other plant sources; it exhibits stimulant, bronchodilatory, anti-asthma, vasoconstrictive, anti-inflammatory, antioxidative, anti-aging, and anti-fibrotic activities. Caffeine activates adenosine receptors and inhibits phosphodiesterases (PDEs), increases levels of cAMP, activating PKA, and inhibiting the release of TNF-α and leukotrienes. 参考文献： Qi H, Li S. Dose-response meta-analysis on coffee, tea and caffeine consumption with risk of Parkinson's disease. Geriatr Gerontol Int. 2014 Apr;14(2):430-9. PMID: 23879665. Gordillo-Bastidas D, Oceguera-Contreras E, Salazar-Montes A, et al. Nrf2 and Snail-1 in the prevention of experimental liver fibrosis by caffeine. World J Gastroenterol. 2013 Dec 21;19(47):9020-33. PMID: 24379627. Herman A, Herman AP. Caffeine's mechanisms of action and its cosmetic use. Skin Pharmacol Physiol. 2013;26(1):8-14. PMID: 23075568. Ribeiro JA, Sebastião AM. Caffeine and adenosine. J Alzheimers Dis. 2010;20 Suppl 1:S3-15. PMID: 20164566. Welsh EJ, Bara A, Barley E, et al. Caffeine for asthma. Cochrane Database Syst Rev. 2010 Jan 20;(1):CD001112. PMID: 20091514. |
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