您的位置:首页>>生化试剂>>小分子化合物>>杀稻瘟素S盐酸盐 Blasticidin S Hydrochloride
Cat. Number
B4402
Chemical Name
杀稻瘟素S盐酸盐 Blasticidin S Hydrochloride
CAS Number
3513-03-9
Mol. Formula
C17H26N8O5 • HCl
Mol. Weight
458.5
Qty 1
25mg
Qty 2
50mg
Appearance
White to off white powder
Application Notes
≥98%
Melting Pt.
224-225°C(dec)
Solubility
Soluble in water. Insoluble in organic solvents.
Storage condition
4°C
References

Blasticidin S is an antibiotic that also exhibits anti-parasitic activity. Blasticidin S inhibits protein synthesis by inducing deformations in P-site tRNA. Blasticidin S inhibits aflatoxin production in species of Aspergillus.

参考文献:

Yoshinari T, Sakuda S, Watanabe M, et al. New metabolic pathway for converting blasticidin S in Aspergillus flavus and inhibitory activity of aflatoxin production by blasticidin S metabolites. J Agric Food Chem. 2013 Aug 21;61(33):7925-31. PMID: 23879927.

 

Svidritskiy E, Ling C, Ermolenko DN, et al. Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12283-8. PMID: 23824292.

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