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Cat. Number
S0046
Chemical Name
Isoquinoline,1,2,3,4-tetrahydro-6,7-dimethoxy-1-methyl
CAS Number
5784-74-7
Mol. Formula
C12H17NO2
Mol. Weight
207.27
Qty 1
25mg
Appearance
Tan Powder
Application Notes
≥98%
Synonym
(±)-Salsolidine
Storage condition
4°C
References

Salsolidine is a tetrahydroisoquinolone alkaloid found in Salsola and other plants. Salsolidine inhibits monoamine oxidase (MAO), acetylcholinesterase (AChE), and buytlcholinesterase (BChE). Salsolidine may inhibit catechol-O-methyltransferase (COMT). Derivatives of salsolidine are neurotoxic and cytotoxic.

References

Talhout R, Opperhuizen A, van Amsterdam JG. Role of acetaldehyde in tobacco smoke addiction. Eur Neuropsychopharmacol. 2007 Oct;17(10):627-36. PMID: 17382522.

Bembenek ME, Abell CW, Chrisey LA, et al. Inhibition of monoamine oxidases A and B by simple isoquinoline alkaloids: racemic and optically active 1,2,3,4-tetrahydro-, 3,4-dihydro-, and fully aromatic isoquinolines. J Med Chem. 1990 Jan;33(1):147-52. PMID: 2296014.

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