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| Cat. Number | A4400 |
| Chemical Name | 丙甲菌素 Alamethicin |
| CAS Number | 27061-78-5 |
| Mol. Formula | C92H150N22O25 |
| Mol. Weight | 1964.4 |
| Qty 1 |
1mg |
| Qty 2 | 5mg |
| Appearance | Off white to beige powder |
| Application Notes | ≥95% |
| Melting Pt. | 255-270°C |
| Solubility | DMSO, Methanol (20 mg/ml), Ethanol (100 mg/ml) |
| Storage condition | 4°C |
| References | 丙甲菌素,Alamethicin is a peptabiol peptide initially produced by species of Trichoderma. Alamethicin is an antimicrobial peptide (AMP) that disturbs the lipid layer of the cell membrane, aggregating and forming pores and causing cell lysis. 参考文献： Krauson AJ, He J, Wimley WC. Determining the mechanism of membrane permeabilizing peptides: identification of potent, equilibrium pore-formers. Biochim Biophys Acta. 2012 Jul;1818(7):1625-32. PMID: 22365969.
Huang HW. Molecular mechanism of antimicrobial peptides: the origin of cooperativity. Biochim Biophys Acta. 2006 Sep;1758(9):1292-302. PMID: 16542637. |
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