服务热线
021-60498804
| Cat. Number | 1502 |
| Chemical Name | 1502 19600-01-2 单唾液酸神经节苷脂GM2,(NH4 +盐) Monosialoganglioside GM2, (NH4+ salt) |
| CAS Number | 19600-01-2 |
| Mol. Formula | C67H121N3O26•NH3 |
| Mol. Weight | 1385+ NH3 |
| Qty 1 |
500µg |
| Appearance | solid |
| Application Notes | 98+%,TLC |
| Synonym | GM2 |
| Solubility | chloroform/methanol/water, 2:1:0.1; forms micellar solution in water |
| Storage condition | -20℃ |
| References | Application Notes: Gangliosides1 are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system.2 They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis, and metastasis.3 GM2 regulates the function of ciliary neurotrophic factor receptors. The accumulation of GM2 (due to a deficiency in beta-hexosaminidase) has characterized Tay-Sachs disease (due to a mutation in the gene HEXA) and Sandhoff disease (due to a mutation in the gene HEXB). A mutation in the GM2A gene results in GM2 activator deficiency that also leads to accumulation of GM2.4
References: |
Copyright © 2022 上海惠诚生物科技有限公司
沪ICP备2021037845号-6
