您的位置:首页>>分析化学>>脂类分析标准品>>1245 2540-56-9 9(Z),11(E)-十八碳二烯酸 9(Z),11(E)-Octadecadienoic acid
Cat. Number
1245
Chemical Name
1245 2540-56-9 9(Z),11(E)-十八碳二烯酸 9(Z),11(E)-Octadecadienoic acid
CAS Number
2540-56-9
Mol. Formula
C18H32O2
Mol. Weight
280
Qty 1
25mg
Appearance
liquid
Application Notes
98+%,GC; TLC; identity confirmed by MS
Synonym
9(Z),11(E)-十八碳二烯酸 9(Z),11(E)-Octadecadienoic acid,9-cis, 11-trans CLA
Solubility
chloroform, ethanol, hexane, methanol, DMSO
Storage condition
-20℃
References

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Application Notes:

9(Z),11(E)-Octadecadienoic acid is a conjugated linoleic acid (CLA), an isomer of linoleic acid. CLA is found mostly in lipids originating in ruminant animals including dairy products. It has several biological properties including anticarcinogenic activity, suppressing in vitro growth of human melanoma, colorectal, and breast cancer cells, and exhibiting anti-atherogenic activity.1 It is thought that CLA itself may not have anti-oxidant capabilities but may produce substances which protect cells from the detrimental effects of peroxides. 9(Z),11(E)-Octadecadienoic acid is the major natural isomer of CLA constituting 73% to 93% of the total CLA in dairy products2 and it appears to be the most biologically active isomer. It appears to enhance animal growth and inhibit osteoclast formation and activity from human cells,3 as well as decrease LDL:HDL and total HDL:cholesterol levels in humans.4

References: 
1. Helen B. MacDonald, Journal of the Amer. College of Nutr., Vol 19, No. 90002, 111S-118S, 2000 
2. M. Belury, Annual Review of Nutrition, July Vol.22, 505, 2002 
3. Ilana Platt, Ahmed El-Sohemy, Lipids in Health and Disease, 8:15, 2009 
4. S. Tricon, et al., The American Journal of Clinical Nutrition, 80:614, 2004



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