服务热线
021-60498804
| Cat. Number | IL1RA |
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Chemical Name | IL1RA Protein, Human, Recombinant (Native) |
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Storage condition | Store it under sterile conditions at -20℃ to -80℃ |
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| References |
白介素1受体拮抗剂(IL1RA)重组蛋白 IL1RA IL1RA Protein, Human, Recombinant (Native)；
惠诚生物提供白介素1受体拮抗剂(IL1RA)重组蛋白 IL1RA以及各类细胞因子，同时推出CHO稳定细胞株开发技术服务方案，详情咨询电话021-60498804白介素1受体拮抗剂(IL1RA)重组蛋白 IL1RA IL1RA Protein, Human, Recombinant (Native)；
白介素1受体拮抗剂(IL1RA)重组蛋白 IL1RA IL1RA Protein, Human, Recombinant (Native)；
惠诚生物提供白介素1受体拮抗剂(IL1RA)重组蛋白 IL1RA以及各类细胞因子，同时推出CHO稳定细胞株开发技术服务方案，详情咨询电话021-60498804.
IL1RA Background Information:
Interleukin-1 receptor antagonist (IL-1RA) also known as IL1RN is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. A polymorphism of this protein encoding gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. IL-1RA/IL1RN may inhibit the activity of IL-1 by binding to its receptor and it has no IL-1 like activity. Genetic variation in IL-1RA/IL1RN is associated with susceptibility to microvascular complications of diabetes type 4 (MVCD4). These are pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis. Defects in IL-1RA/IL1RN are the cause of interleukin 1 receptor antagonist deficiency (DIRA) which is also known as deficiency of interleukin 1 receptor antagonist. Autoinflammatory diseases manifest inflammation without evidence of infection, high-titer autoantibodies, or autoreactive T-cells. DIRA is a rare, autosomal recessive, genetic autoinflammatory disease that results in sterile multifocal osteomyelitis, and pustulosis from birth.
上海惠诚生物科技有限公司成立于2010年，历经多年的积累，现推出CHO稳定细胞株开发技术服务方案，详情请咨询电话021-60498804.
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Copyright © 2022 上海惠诚生物科技有限公司
沪ICP备2021037845号-6
