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| Cat. Number | 1049 |
| Chemical Name | 1049 85496-63-5硫苷脂 Sulfatides |
| CAS Number | 85496-63-5 |
| Mol. Formula | C42H80NNaO11S |
| Mol. Weight | 830 (stearoyl) Na+ Salt |
| Qty 1 |
50mg |
| Appearance | solid |
| Application Notes | 98+%,TLC; identity confirmed by MS |
| Synonym | 硫苷脂 Sulfatides, |
| Storage condition | -20℃ |
| References | Application Notes: Sulfatide is a type of sulfolipid that is found primarily in the central nervous system and is a myelin-specific sphingolipid. A deficiency of sulfatide in white and gray matter has been associated with Alzheimer’s disease and other types of dementia. Apoliprotein E plays an important regulating role in the metabolism of sulfatides.1 A production of anti-sulfatide antibodies in the cerebrospinal fluid, leading to a deficiency in sulfatides, may be a cause of degeneration of the myelin sheath, leading to multiple sclerosis.2 Metachromatic leukodystrophy is an inherited disorder characterized by a deficiency of the lysosomal enzyme arylsulfatase A and the subsequent accumulation of sulfatide in neural and visceral tissues.3 An immunomodulatory role for sulfatides has been suggested in the pathogenesis of tuberculosis.
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