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Cat. Number
Aprotinin
Chemical Name
Aprotinin
CAS Number
9087-70-1
Category
Inhibitor
Mol. Formula
C284H432N84O79S7
Mol. Weight
6511.44
Qty 1
100mg
Qty 2
500mg
Application Notes
≥95%
Synonym
Bovine Pancreatic Trypsin Inhibitor,BPTI,Trasylol
Storage condition
2-8°C
References

Aprotinin is a reversible inhibitor of serine proteases such as trypsin (Ki = 0.06 pM), chymotrypsin (Ki = 9.5 nM), and kallikrein (Ki = 0.8 nM).1 It is a much weaker inhibitor of thrombin (Ki = 0.1-0.8 mM) and trypsinogen (Ki = 2 µM).1 Aprotinin also competitively inhibits nNOS and iNOS with Ki values of 50 and 78 µM, respectively.2 Aprotinin is widely used as a protein purification tool to prevent proteases present in tissue samples from degrading the protein of interest.

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