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Cat. Number
马铃薯葡萄糖琼脂(PDA)(添加抗生素)Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO
Chemical Name
马铃薯葡萄糖琼脂(PDA)(添加抗生素)Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO
Mol. Formula
C30H30CuN10O4S
Mol. Weight
690.23
Qty 1
1.5mL
Appearance
blue solution
Storage condition
-20°C
References

Copper (II)-TBTA complex is a component of catalyst used for Click Chemistry conjugation reaction. Actual catalyst contains Cu(I), but this reagent cannot be stored, and should be generated from Copper(II)-TBTA complex in situ by reduction. To activate this catalyst, reductant such as ascorbic acid should be added to reaction mixture.

Cu-TBTA complex structure

Product citations

  1. Routh, A.; Ji, P.; Jaworski, E.; Xia, Z.; Li, W.; Wagner, E.J. Poly(A)-ClickSeq: click-chemistry for next-generation 3′-end sequencing without RNA enrichment or fragmentation. BioRxiv, in press. doi:10.1101/109272

  2. Taskova, M.; Madsen, C.S.; Jensen, K.J.; Hansen, L.H.; Vester, B.; Astakhova, K. Antisense oligonucleotides internally labeled with peptides show improved target recognition and stability to enzymatic degradation. Bioconjugate Chemistry, 2017, 28(3), 768–774. doi: 10.1021/acs.bioconjchem.6b00567

  3. Long, M.J.C.; Parvez, S.; Zhao, Y.; Surya, S.L.; Wang, Y.; Zhang, S.; Aye, Y. Akt3 is a privileged first responder in isozyme-specific electrophile response. Nature Chemical Biology, 2017, 13(3), 333–338. doi:10.1038/nchembio.2284

  4. Shi, P.; Ju, E.; Yan, Z.; Gao, N.; Wang, J.; Hou, J.; Zhang, Y.; Ren, J.; Qu, X. Spatiotemporal control of cell-cell reversible interactions using molecular engineering. Nature communications, 2016, 7, 13088. doi:10.1038/ncomms13088
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