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Cat. Number
炔烃CPG修饰剂 500 Alkyne CPG modifier 500
Chemical Name
炔烃CPG修饰剂 500 Alkyne CPG modifier 500
Qty 1
250mg
Qty 2
500mg
Appearance
off-white beads
Storage condition
-20°C
References

High loading controlled pore glass solid support for the synthesis of oligonucleotides with 3'-alkyne group. With this solid support, synthesis of oligos of up to 50 bases is possible.

Terminal alkyne group can be modified by copper catalyzed Click chemistry (see our recommended protocolfor oligonucleotide modification).

This solid support is compatible with standard oligonucleotide deblocking conditions. No special deblocking is required.

Alkyne CPG modifier controlled pore glass structure
 
 

Oligo synthesis details

Pore size, Å: 500
Typical loading, umol/g: 70−90
Coupling conditions: standard coupling, identical to normal nucleobases
Cleavage conditions: ammonia, 2 h at room temperature
Deprotection conditions: identical to protected nucleobases