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Cat. Number
生物素叠氮化物 Biotin azide
Chemical Name
生物素叠氮化物 Biotin azide
Mol. Formula
C16H28N6O4S
Mol. Weight
400.50
Qty 1
25mg
Qty 2
50mg
Appearance
colorless solid
Solubility
soluble in DMF, DMSO, moderately soluble in water
Storage condition
-20°C
References

Biotin azide is a derivative of biotin (vitamin H) covalently bound with azide group. This reagent allows labeling of various alkynylated molecules (such as DNA, oligonucleotides, and proteins) with biotin. Biotin binding to avidin or streptavidin can be used in downstream affinity applications for the isolation of biotinylated molecules or their binding with streptavidin conjugates.

This structure of biotin azide features long hydrophilic linker which separates biotin residue from the target molecule for efficient binding with streptavidin. Its linker (PEG) also enhances aquous solubility to facilitate conjugation.

The azide can be conjugated with various molecules using our recommended protocol.

Product citations

  1. Bruckman, M.A.; Czapar, A.E.; VanMeter, A.; Randolph, L.N.; Steinmetz, N.F. Tobacco mosaic virus-based protein nanoparticles and nanorods for chemotherapy delivery targeting breast cancer. Journal of Controlled Release2016, 231, 103–113. doi: 10.1016/j.jconrel.2016.02.045